RUMORED BUZZ ON MAKATUSSIN SYROP

desvenlafaxine will boost the stage or effect of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Caution/Watch. Desvenlafaxine inhibits CYP2D6; with greater desvenlafaxine doses (ie, 400 mg) lessen the CYP2D6 substrate dose by up to 50%; no dosage adjustment wanted with desvenlafaxine doses 7 consecutive times immediately prior to using